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2021

• Nakamura M, Uemura K, Saito-Tarashima N, Sato A, Orba Y, Sawa H, Matsuda A, Maenaka K, Minakawa N.
  Synthesis and Anti-dengue Virus Activity of 5-Ethynylimidazole-4-carboxamide (EICA) Nucleotide Prodrugs.
  Chem Pharm Bull (Tokyo). 2022 Mar 1;70(3):220-225. doi: 10.1248/cpb.c21-01038. Epub 2021 Dec 25.
  PMID: 34955490
• Hasegawa T, Imamura RM, Suzuki T, Hashiguchi T, Nomura T, Otsuguro S, Maenaka K, Sasaki M, Orba Y, Sawa H, Sato A, Okabe T, Nagano T, Kojima H.
  Application of Acoustic Ejection MS System to High-Throughput Screening for SARS-CoV-2 3CL Protease Inhibitors.
  Chem Pharm Bull (Tokyo). 2022 Mar 1;70(3):199-201. doi: 10.1248/cpb.c21-01003. Epub 2021 Dec 21.
  PMID: 34937844
• Matsumaru T, Ikeno R, Shuchi Y, Iwamatsu T, Tadokoro T, Yamasaki S, Fujimoto Y, Furukawa A, Maenaka K.
  Correction: Synthesis of glycerolipids containing simple linear acyl chains or aromatic rings and evaluation of their Mincle signaling activity.
  Chem Commun (Camb). 2022 Feb 17;58(15):2580. doi: 10.1039/d2cc90023h.
  PMID: 35113118
• Ozawa T, Tani H, Anraku Y, Kita S, Igarashi E, Saga Y, Inasaki N, Kawasuji H, Yamada H, Sasaki SI, Somekawa M, Sasaki J, Hayakawa Y, Yamamoto Y, Morinaga Y, Kurosawa N, Isobe M, Fukuhara H, Maenaka K, Hashiguchi T, Kishi H, Kitajima I, Saito S, Niimi H.
  Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants.
  MAbs. 2022 Jan-Dec;14(1):2072455. doi: 10.1080/19420862.2022.2072455.
  PMID: 35543180
• Kuroki K, Fukuhara H, Tadokoro T, Maenaka K.
  Low-Cost Cell-Surface-Mimic Analysis of Ligand Interactions of Biotinylated Immune Receptors Using Surface Plasmon Resonance.
  Methods Mol Biol. 2022;2421:21-35. doi: 10.1007/978-1-0716-1944-5_2.
  PMID: 34870809
• Yumoto K, Arisaka T, Okada K, Aoki K, Ose T, Masatani T, Sugiyama M, Ito N, Fukuhara H, Maenaka K.
  Characterization of Single-Chain Fv Fragments of Neutralizing Antibodies to Rabies Virus Glycoprotein.
  Viruses. 2021 Nov 19;13(11):2311. doi: 10.3390/v13112311.
  PMID: 34835117
• Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K.
  5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
  iScience. 2021 Oct 22;24(10):103120. doi: 10.1016/j.isci.2021.103120. Epub 2021 Sep 11.
  PMID: 34541466
• Onodera T, Kita S, Adachi Y, Moriyama S, Sato A, Nomura T, Sakakibara S, Inoue T, Tadokoro T, Anraku　Y, Yumoto K, Tian C, Fukuhara H, Sasaki M, Orba Y, Shiwa N, Iwata N, Nagata N, Suzuki T, Sasaki J,　Sekizuka T, Tonouchi T, Sun L, Fukushi S, Satofuka H, Kazuki Y, Oshimura M, Kurosaki T, Kuroda M,　Matsuura Y, Suzuki T, Sawa H, Hashiguchi T, Maenaka K, Takahashi Y.
  A SARS-CoV-2 Antibody Broadly Neutralizes SARS-related Coronaviruses and Variants by Coordinated Recognition of a Virus Vulnerable Site.
  Immunity. 2021 Oct 12;54(10):2385-2398.e10. doi: 10.1016/j.immuni.2021.08.025. Epub 2021 Aug 24. PMID: 34508662
• Tomita Y, Matsuyama S, Fukuhara H, Maenaka K, Kataoka H, Hashiguchi T, Takeda M.
  The Physiological TMPRSS2 Inhibitor HAI-2 Alleviates SARS-CoV-2 Infection.
  J Virol. 2021 May 24;95(12):e00434-21. doi: 10.1128/JVI.00434-21. Print 2021 May 24. PMID: 33789993
• Tanikawa Y, Kanemura S, Ito D, Lin Y, Matsusaki M, Kuroki K, Yamaguchi H, Maenaka K, Lee YH, Inaba K, Okumura M.
  Ca²⁺ Regulates ERp57-Calnexin Complex Formation.
  Molecules. 2021 May 11;26(10):2853. doi: 10.3390/molecules26102853. PMID: 34064874
• Ohashi H, Watashi K, Saso W, Shionoya K, Iwanami S, Hirokawa T, Shirai T, Kanaya S, Ito Y, Kim KS, Nomura T, Suzuki T, Nishioka K, Ando S, Ejima K, Koizumi Y, Tanaka T, Aoki S, Kuramochi K, Suzuki T, Hashiguchi T, Maenaka K, Matano T, Muramatsu M, Saijo M, Aihara K, Iwami S, Takeda M, McKeating JA, Wakita T.
  Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment.
  iScience. 2021 Apr 23;24(4):102367. doi: 10.1016/j.isci.2021.102367. Epub 2021 Mar 26. PMID: 33817567
• Yoshida T, Yamagata A, Imai A, Kim J, Izumi H, Nakashima S, Shiroshima T, Maeda A, Iwasawa-Okamoto S, Azechi K, Osaka F, Saitoh T, Maenaka K, Shimada T, Fukata Y, Fukata M, Matsumoto J, Nishijo H, Takao K, Tanaka S, Okabe S, Tabuchi K, Uemura T, Mishina M, Mori H, Fukai S.
  Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
  Nat Commun. 2021 Mar 23;12(1):1848. doi: 10.1038/s41467-021-22059-6. PMID: 33758193
• Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A.
  MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2.
  Sci Rep. 2021 Mar 8;11(1):5376. doi: 10.1038/s41598-021-84882-7. PMID: 33686154
• Miyachi H, Kanamitsu K, Ishii M, Watanabe E, Katsuyama A, Otsuguro S, Yakushiji F, Watanabe M, Matsui K, Sato Y, Shuto S, Tadokoro T, Kita S, Matsumaru T, Matsuda A, Hirose T, Iwatsuki M, Shigeta Y, Nagano T, Kojima H, Ichikawa S, Sunazuka T, Maenaka K.
  Structure, solubility, and permeability relationships in a diverse middle molecule library.
  Bioorg Med Chem Lett. 2021 Apr 1;37:127847. doi: 10.1016/j.bmcl.2021.127847. Epub 2021 Feb 9. PMID: 33571648
• Sasaki M, Uemura K, Sato A, Toba S, Sanaki T, Maenaka K, Hall WW, Orba Y, Sawa H.
  SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells.
  PLoS Pathog. 2021 Jan 21;17(1):e1009233. doi: 10.1371/journal.ppat.1009233. eCollection 2021 Jan. PMID: 33476327

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