2023
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Protein kinase Cβ is involved in cigarette smoke gas phase-induced ferroptosis in J774 macrophages.
Higashi T, Handa H, Mai Y, Maenaka K, Tadokoro T.
J Pharmacol Sci. 2023 Sep;153(1):22-25. doi: 10.1016/j.jphs.2023.06.001. Epub 2023 Jun 21.
PMID: 37524450
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Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants.
Moriyama S, Anraku Y, Taminishi S, Adachi Y, Kuroda D, Kita S, Higuchi Y, Kirita Y, Kotaki R, Tonouchi K, Yumoto K, Suzuki T, Someya T, Fukuhara H, Kuroda Y, Yamamoto T, Onodera T, Fukushi S, Maeda K, Nakamura-Uchiyama F, Hashiguchi T, Hoshino A, Maenaka K, Takahashi Y.
Nat Commun. 2023 Jul 14;14(1):4198. doi: 10.1038/s41467-023-39890-8.
PMID: 37452031
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Structural basis for plastic glycolipid recognition of the C-type lectin Mincle.
Furukawa A, Shuchi Y, Wang J, Guillen-Poza PA, Ishizuka S, Kagoshima M, Ikeno R, Kumeta H, Yamasaki S, Matsumaru T, Saitoh T, Maenaka K.
Structure. 2023 Jun 11:S0969-2126(23)00194-6. doi: 10.1016/j.str.2023.05.018. Online ahead of print.
PMID: 37348496
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Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants.
Tamura T, Ito J, Uriu K, Zahradnik J, Kida I, Anraku Y, Nasser H, Shofa M, Oda Y, Lytras S, Nao N, Itakura Y, Deguchi S, Suzuki R, Wang L, Begum MM, Kita S, Yajima H, Sasaki J, Sasaki-Tabata K, Shimizu R, Tsuda M, Kosugi Y, Fujita S, Pan L, Sauter D, Yoshimatsu K, Suzuki S, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Yamamoto Y, Nagamoto T, Schreiber G, Maenaka K; Genotype to Phenotype Japan (G2P-Japan) Consortium; Hashiguchi T, Ikeda T, Fukuhara T, Saito A, Tanaka S, Matsuno K, Takayama K, Sato K.
Nat Commun. 2023 May 16;14(1):2800. doi: 10.1038/s41467-023-38435-3.
PMID: 37193706
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Ready-to-Use-Type Lyophilized Lipid Nanoparticle Formulation for the Postencapsulation of Messenger RNA.
Tanaka H, Hagiwara S, Shirane D, Yamakawa T, Sato Y, Matsumoto C, Ishizaki K, Hishinuma M, Chida K, Sasaki K, Yonemochi E, Ueda K, Higashi K, Moribe K, Tadokoro T, Maenaka K,, Taneichi S, Nakai Y, Tange K, Sakurai Y, Akita
H.ACS Nano. 2023 Feb 14;17(3):2588-2601. doi: 10.1021/acsnano.2c10501. Epub 2023 Jan 31.
PMID: 36719091
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2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses.
Uemura K, Nobori H, Sato A, Toba S, Kusakabe S, Sasaki M, Tabata K, Matsuno K, Maeda N, Ito S, Tanaka M, Anraku Y, Kita S, Ishii M, Kanamitsu K, Orba Y, Matsuura Y, Hall WW, Sawa H, Kida H, Matsuda A, Maenaka K
Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2304139120. doi: 10.1073/pnas.2304139120. Epub 2023 Oct 13.
PMID: 37831739
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Beneficial effects of a new neuroprotective compound in neuronal cells and MPTP-
administered mouse model of Parkinson's disease.
Kato I, Ogawa Y, Yakushiji F, Ogura J, Kobayashi M, Shindo N, Ichikawa S, Maenaka
K, Sakaitani M.Chem Commun (Camb). 2023 Oct 12;59(82):12306-12309. doi:
10.1039/d3cc03069e.
PMID: 37753573
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An Electron-Deficient CpE Iridium(III) Catalyst: Synthesis, Characterization, and Application to Ether-Directed C-H Amidation.
Tomita E, Kojima M, Nagashima Y, Tanaka K, Sugiyama H, Segawa Y, Furukawa A, Maenaka K, Maeda S, Yoshino T, Matsunaga S.Angew
Chem Int Ed Engl. 2023 May 15;62(21):e202301259. doi: 10.1002/anie.202301259. Epub 2023 Apr 14.
PMID: 36918357
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Corrigendum: Intraocular human cytomegaloviruses of ocular diseases are distinct from those of viremia and are capable of escaping from innate and adaptive immunity by exploiting HLA-E-mediated peripheral and central tolerance.
Shirane M, Yawata N, Motooka D, Shibata K, Khor SS, Omae Y, Kaburaki T, Yanai R, Mashimo H, Yamana S, Ito T, Hayashida A, Mori Y, Numata A, Murakami Y, Fujiwara K, Ohguro N, Hosogai M, Akiyama M, Hasegawa E, Paley M, Takeda A, Maenaka K, Akashi K, Yokoyama WM, Tokunaga K, Yawata M, Sonoda KH.Front Immunol. 2023 Jan 5;13:1124440. doi: 10.3389/fimmu.2022.1124440. eCollection 2022..
PMID: 36685570
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新型コロナウイルス感染症に対する抗体医薬品の開発
喜多俊介、 前仲勝実
道薬誌ブラッシュアップ講座 (2023年11月)